Comparison of the effect of surgical site skin preparation with povidone-iodine solution at two different temperatures on the antimicrobial effect and surgical wound infectio

Phase 3

Conditions: Surgical site infection.

Registration Number: IRCT20240212060966N1

Lead Sponsor: Iran University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: All

Target Recruitment: 126

Inclusion Criteria

Age 18 to 55 years
Having at least a diploma degree
No diabetes
No history of laparotomy surgery
Body mass index less than 35
Absence of immune system deficiency and no use of immunosuppressive drugs
Absence of local infection near the surgical site or systemic infection
Not being allergic to povidone-iodine antiseptic
No history of malignancy and radiation therapy
Absence of severe skin rash at the surgical site
Not using broad-spectrum antibiotics within a month before going to the hospital
having Elective surgery

Exclusion Criteria

Emergency laparotomy surgery
Disruption in the surgical process that leads to the contamination of the instruments or the surgical field
immune system deficiency and using immunosuppressive drugs
having diabetes
allergic to povidone-iodine antiseptic
The presence of rashes and severe skin diseases at the surgical site
using broad-spectrum antibiotics within a month before going to the hospital
morbid obesity

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Microbial load. Timepoint: microbial cultures will be taken in three stages before the surgical site skin preparation, after the initial stage of disinfection of the surgical site and after the secondary stage of disinfection of the surgical site with povidone-iodine 10%. Method of measurement: taking microbial culture and counting microbial colonies 24 hours after incubation.;Surgical site infection. Timepoint: Observation and examination of the surgical wound after 24 hours and 30 days after surgery. Method of measurement: Observing and examining the surgical wound and entering the symptoms in the surgical site infection checklist.

Secondary Outcome Measures