The Effect of Cervical Proprioceptive Neuromuscular Facilitation along with Pressure Biofeedback on improving Severity, Range of Motion and Quality of Life in patients with Chronic Cervical Dystonia A Pre Post Interventional study
概览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- Dr Tanisha Mali
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- 1. Cervical Dystonia: Toronto Western Spasmodic
概览
简要总结
Title
The Effect of Cervical Proprioceptive Neuromuscular Facilitation along with Pressure Biofeedback on improving Severity, Range of Motion and Quality of Life in patients with chronic Cervical Dystonia – a pre-post interventional study
Overview
This study investigates the combined effect of Cervical Proprioceptive Neuromuscular Facilitation (PNF) and Pressure Biofeedback in patients with chronic Cervical Dystonia (CD), a neurological movement disorder characterized by involuntary muscle contractions in the neck, leading to abnormal postures, pain, reduced range of motion (ROM), and diminished quality of life (QoL).
Objectives
To assess whether the intervention improves:
-
Severity of cervical dystonia
-
Range of motion of the cervical spine
-
Quality of life of affected individuals
Rationale
Current first-line treatments like Botulinum Toxin injections provide symptomatic relief but often leave residual disability. There is limited research on combining PNF with pressure biofeedback as a therapeutic alternative for CD.
Methodology
Design: Pre-post interventional study
Sample Size: 25 participants
Duration: 8 weeks - 3 sessions per week
Population: Adults aged 20 to 60 with chronic CD, diagnosed greater than 1 year, TWSTRS score more than 35, no BoNT in last 6 months
Tools Used:
-
CD Severity Scale (CDSS) for severity
-
Goniometer for ROM
-
CDQoL-24 Questionnaire for quality of life
-
TWSTRS for baseline inclusion
Intervention
PNF: Targeting cervical flexors, extensors, lateral flexors, and rotators using the Contract Relax Antagonist Contract (CRAC) technique
Pressure Biofeedback: Sub-occipital positioning of a pressure sensor to facilitate deep neck flexor activation and control
Data Analysis
Pre- and post-intervention data will be compared using Paired t-test or Wilcoxon Signed Rank Test depending on data normality.
p-value less than 0.05 considered significant.
Data analyzed using SPSS v29
Primary Hypothesis
Null Hypothesis (H0)
There will be no significant effect of Cervical Proprioceptive Neuromuscular Facilitation along with Pressure Biofeedback on severity, range of motion, and quality of life in patients with chronic Cervical Dystonia.
Alternative Hypothesis (H1)
There will be a significant effect of Cervical Proprioceptive Neuromuscular Facilitation along with Pressure Biofeedback on severity, range of motion, and quality of life in patients with chronic Cervical Dystonia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •Individuals with chronic (1 year post symptoms) Cervical Dystonia.
- •Diagnosed with cervical dystonia by a physician.
- •Age group of 20-60 years
- •Both the genders
- •Individuals with Toronto Western Spasmodic Torticollis Rating Scale score of minimum
- •No history of Botulinum Toxin Injection taken in past 6 months.
排除标准
- •Individuals with acute Cervical Dystonia.
- •Individuals persisting other cervical deformities along with cervical dystonia.
- •Participants who have taken Botulinum Toxin Injection in less than past 6 months span.
结局指标
主要结局
1. Cervical Dystonia: Toronto Western Spasmodic
时间窗: 1. baseline data: 1st day of treatment | 2. Final data: after 8 weeks of treatment which will be the result data.
Torticollis Rating Scale.
时间窗: 1. baseline data: 1st day of treatment | 2. Final data: after 8 weeks of treatment which will be the result data.
2. Severity: Cervical Dystonia Severity Scale (CDSS)
时间窗: 1. baseline data: 1st day of treatment | 2. Final data: after 8 weeks of treatment which will be the result data.
3. Range of Motion: Goniometry
时间窗: 1. baseline data: 1st day of treatment | 2. Final data: after 8 weeks of treatment which will be the result data.
4. Quality of Life: Cervical Dystonia questionnaire 24
时间窗: 1. baseline data: 1st day of treatment | 2. Final data: after 8 weeks of treatment which will be the result data.
(CDQ-24)
时间窗: 1. baseline data: 1st day of treatment | 2. Final data: after 8 weeks of treatment which will be the result data.
次要结局
未报告次要终点
研究者
Dr Tanisha Mali
Dr. G. D. Pol Foundation, YMT College of Physiotherapy