Granisetron and incidence of shivering in children after spinal anesthesia

Phase 4

Completed

• Conditions: shivering during spinal anesthesia in children; Anaesthesiology - Anaesthetics

• Registration Number: ACTRN12611001059954
• Lead Sponsor: Yasser M. Amr

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-10-11
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

80 children ASA 1 and 2 scheduled for lower limb surgery under spinal anaesthesia were entered into study

Exclusion Criteria

Exclusion criteria included: refusal of parents, coagulopathy, spinal congenital anomalies, neurological abnormality, allergy to local anesthetics and surgery scheduled to last for more than 90 minutes, children with hypo or hyperthyroidism, children with hypothermia or hyperthermia and those who needed intraoperative blood transfusion.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of shivering<br>Shivering was assessed using scale of Tsai and Chu. <br> 0 no shivering<br>1 Mild fasciculations of face or neck<br>2 Visible tremor involving more than one muscle group<br>3 Gross muscular activity involving the entire body[shivering were recorded before spinal anesthesia, 15, 30, 60& 90 min. after spinal anesthesia.]

Secondary Outcome Measures

Name	Time	Method
Motor block was assessed using the Bromage scale recording the ability to flex hip, knee and ankle.[10 minute after injection of bupivacaine];Sensory block was assessed by bilateral pin prick at each dermatome to elicit grimace or acknowledgement of pain.[10 minute after injection of bupivacaine]