Can Intravenous Vitamin C Improve Skin Hyperpigmentation in Long-Term Hemodialysis Patients?

Not Applicable

• Conditions: Kidney Failure, Chronic

• Registration Number: NCT00172302
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

Intravenous vitamin C may improve skin hyperpigmentation in chronic hemodialysis patients

Detailed Description

Melanogenesis is caused by enzymatic conversion of tyrosine to melanin pigments.Ascorbic acid has the ability to inhibit peroxidase and may thus inhibit melanin synthesis.

Study Timeline

• Status Verified: 2005-05
• Study First Submitted: 2005-09-12
• Study First Submitted QC: 2005-09-12
• Last Update Submitted: 2005-09-12
• Study First Posted: 2005-09-15
• Last Update Posted: 2005-09-15
• Study Start: 2005-11

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• chronic hemodialysis patients

Exclusion Criteria

• allergic to vitamin C, using steroid, etc

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Skin pigmentation extent

Secondary Outcome Measures

Name	Time	Method
blood anti-oxidant level

Trial Locations

Locations (1)

National Taiwan University Hospital; 🇨🇳 Taipei, Taiwan