6-month Efficacy of Ultrasound-guided Injection of 5% Dextrose for Meralgia Paresthesia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- visual analogue scale(VAS)
研究概览
简要总结
Meralgia paresthetica (MP) is one of the most common peripheral entrapment neuropathies of the lower limbs. It is characterized by paresthesia, pain, tingling, numbness, hypersensitivity, or other abnormal skin sensations on the anterolateral aspect of the thigh. The condition results from compression of the lateral femoral cutaneous nerve (LFCN) along its course, often occurring as the nerve exits the pelvis.The injection of 5% dextrose (D5W) under ultrasound guidance is a novel treatment method for peripheral nerve entrapment. However, there is limited evidence about the efficacy of this method for patients with MP. The investigators found D5W was more safe and effective than corticosteroids for patients with MP. Thus, this study aimed to evaluate the 6-month efficacy of ultrasound-guided injection of D5W for MP patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients aged between 18 and 80 years;
- •those diagnosed with MP based on clinical and physical examination, with symptoms persisting for at least 3 months;
- •a high-resolution ultrasound revealing LFCN compression as it exited the pelvis.
排除标准
- •MP resulting from trauma, surgery or occupying lesions affecting the LFCN;
- •pregnancy;
- •concurrent presence of rheumatic immune diseases, hypothyroidism, or diabetes mellitus;
- •a known history of allergy to lidocaine or corticosteroids;
- •L2/3 lumbar radiculopathy;
- •patients who had undergone local injection or surgery for MP within 3 months
结局指标
主要结局
visual analogue scale(VAS)
时间窗: baseline as well as 1month, 3 month, 6 months post-injection
VAS is one of the most common tool to assess pain severity for patients, ranging from 0(no pain) to 10(most possible pain).
次要结局
- cross-sectional area(CSA) of the nerve(baseline as well as 1month, 3 month, 6 months post-injection)
研究者
Zhu Jiaan
Professor
Peking University People's Hospital