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临床试验/NCT06720103
NCT06720103尚未招募不适用

Correlation Between Radiculopathy And Quality Of Life In Patients With Chronic Lumbar Spondylosis

Cairo University0 个研究点目标入组 132 人开始时间: 2024年12月20日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
132
主要终点
life disability

研究概览

简要总结

This study will be conducted to answer the following question:

Is there a Correlation Between Lumbar Radiculopathy and Quality of Life in Patients with chronic lumbar spondylosis?

详细描述

Spondylosis is an age-related change of vertebrae and discs of the spine. These changes are often called degenerative disc disease and osteoarthritis. When this condition is in the lower back, it's called lumbar spondylosis.

Lumbar osteoarthritis, disc degeneration, degenerative disc disease, and spondylosis are some of the terms used to describe disc changes. In fact, the condition is called spondylosis. Whenever there is a degeneration co-occurrence in the disc, the lumbar spine, the formation of osteophytes and the associated changes in the nerves and the resulting symptoms of pain.Spinal osteoarthritis (OA) is a degenerative process defined radiologically by joint space narrowing, osteophytosis, subchondral sclerosis, and cyst formation.

Osteophytes included within this definition fall into one of the two primary clinical categories.

The first, spondylosis deforms describes bony outgrowths arising primarily along the anterior and lateral perimeters of the vertebral endplate apophyses. These hypertrophic changes are believed to develop at sites of stress to the annular ligament and most commonly occur at thoracic T9-10 and lumbar L3 levels.These conditions lead to nerve root compression, resulting in radiating pain down the leg, commonly referred to as sciatica. The impact of lumbar radiculopathy extends beyond pain, affecting muscle function and neuromuscular control. The involvement of nerve roots such as L4, L5, and S1 can particularly affect the muscles in the lower extremities, including the plantar flexor muscles, which are crucial for movements like walking, running, and maintaining balance

研究设计

研究类型
Observational
观察模型
Other
时间视角
Cross Sectional

入排标准

年龄范围
30 Years 至 50 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • All patient diagnosed and referred from a physician
  • Patients suffered from lumbar spondylosis (L4: L5) with radiculopathy more than 3 months
  • Participants will be from both gender
  • Age will be ranged from 30 to
  • BMI of all participants ≤ 30 kg/m2

排除标准

  • Pregnant and breast-feeding women
  • Patients diagnosed with depression and anxiety
  • Patient who had undergone lumbar spine surgery
  • People with systemic illnesses or physical deformities

结局指标

主要结局

life disability

时间窗: up to one day

WHOQOL questionnaire will be used to assess life disability. it is defined as the individual's perception of their QoL. It consists of 24 questions which cover 4 categories plus 2 questions related to scale and health satisfaction. Each individual item of the WHOQOL-BRIEF is scored from 1 to 5 on a response scale, which is stipulated as a five-point ordinal scale. The scores are then transformed linearly to a 0-100-scale.

次要结局

  • sciatic radiculopathy(up to one day)
  • mechanosensitivity of the neuromeningeal structures within the vertebral canal(up to one day)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mona Abdelmageed Ali

principale investigator: mona abdelmageed ali

Cairo University

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