Dexamethasone Phonophoresis Versus Laser Acupuncture on Chronic Rhinosinusitis
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 入组人数
- 90
- 试验地点
- 2
- 主要终点
- Sino nasal Outcome Test 22 (SNOT-22)
研究概览
简要总结
This study is designed to provide a comprehensive overview of evidence concerning the efficacy and safety of dexamethasone phonophoresis and laser acupuncture for treatment of chronic rhinosinusitis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 30 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age range between 30 to 50 years.
- •Male and female patients will participate in the study.
- •All patients have chronic rhinosinusitis, who are experiencing 12 weeks or longer of 2 or more of the following signs and symptoms:
- •mucopurulent drainage (anterior, posterior, or both) nasal obstruction (congestion) facial pain-pressure-fullness, or decreased sense of smell
- •All patients enrolled in the study will have their informed consent.
排除标准
- •Patients with metal implants (pacemakers, dental implants, or any other implants).
- •Patients with cancer, pregnancy or impaired vascular circulation.
- •Patients who suffer from mental or psychological disorders.
- •Patients with any systemic diseases that may interfere with the objectives of the study.
- •Patients with long-term use of corticosteroids or immunosuppressive agents.
- •Congenital defects on face and nose.
- •Fracture of nose or face.
- •Patients who are contraindicated for corticosteroids use in patient who will receive dexamethasone phonophoresis.
- •Allergic patients.
- •Pervious nasal surgery.
- •Patients with nasal septum deviation.
- •patients who had used antihistamines within 1 week, topical corticosteroids within2 weeks, systemic corticosteroids within 4 weeks, anti-cholinergic drugs within 3 days, antileukotriene drugs within 1 week, decongestants within 3 days, tricyclic antidepressants or phenothiazines within 2 weeks, non-steroidal analgesics within 2 weeks or any medication that may interfere with the objectives of the study.
结局指标
主要结局
Sino nasal Outcome Test 22 (SNOT-22)
时间窗: one month
This is a Quality Of Life Questionnaire specifically designed for sinusitis patient. It consists of 22 item sinus specific question which has to be administered to the patient and the total sum of all the items will be recorded based on the severity of the patient's condition and the scores will be calculated
Computerized Tomography Scan
时间窗: one month
CT scan will be used for assessment of mucosal thickening of maxillary sinuses, which is based on 0-3 system: 0 = clear, 1= mild or moderate mucosal thickening, 2 = severe mucosal thickening, 3 = total opacification
次要结局
未报告次要终点
研究者
Walaa Abd Elaziem Abd Elaziz
Walaa Abd Elaziem Abd Elaziz
Cairo University