Autologous Bone Marrow Stem Cells Transplantation in Patients With Temporal Lobe Epilepsy
Phase 1
Completed
- Conditions
- Epilepsy
- Registration Number
- NCT00916266
- Lead Sponsor
- Instituto do Cerebro de Brasilia
- Brief Summary
This research investigates the use of autologous bone marrow stem cells for the treatment of medically refractory temporal lobe epilepsy patients.
- Detailed Description
The aim of this study is to evaluate autologous bone marrow stem cells transplantation as a safe and potentially beneficial treatment for patients with temporal lobe refractory epilepsy. We are mainly evaluating seizure frequency, hippocampal volume an cognitive performance
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
- temporal lobe medically refractory epilepsy patients with hippocampal atrophy
Exclusion Criteria
- under 18 or over 65 years old patients
- previous neurological surgery
- other neurodegenerative diseases
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method seizure frequency 6 months
- Secondary Outcome Measures
Name Time Method adverse effects 6 months hippocampal volume 6 months cognitive performance 6 months
Trial Locations
- Locations (1)
Instituto do Cerebro
🇧🇷Porto Alegre, RS, Brazil
Instituto do Cerebro🇧🇷Porto Alegre, RS, Brazil