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Clinical Trials/NCT00916266
NCT00916266
Completed
Phase 1

Phase 1 Study of Autologous Bone Marrow Stem Cells Transplantation in Patients With Temporal Lobe Epilepsy

Instituto do Cerebro de Brasilia1 site in 1 country20 target enrollmentJuly 2008
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ConditionsEpilepsy

Overview

Phase
Phase 1
Intervention
Not specified
Conditions
Epilepsy
Sponsor
Instituto do Cerebro de Brasilia
Enrollment
20
Locations
1
Primary Endpoint
seizure frequency
Status
Completed
Last Updated
10 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

This research investigates the use of autologous bone marrow stem cells for the treatment of medically refractory temporal lobe epilepsy patients.

Detailed Description

The aim of this study is to evaluate autologous bone marrow stem cells transplantation as a safe and potentially beneficial treatment for patients with temporal lobe refractory epilepsy. We are mainly evaluating seizure frequency, hippocampal volume an cognitive performance

Registry
clinicaltrials.gov
Start Date
July 2008
End Date
May 2012
Last Updated
10 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Instituto do Cerebro de Brasilia
Responsible Party
Principal Investigator
Principal Investigator

Jaderson Costa da Costa

MD, PhD

Hospital Sao Lucas da PUCRS

Eligibility Criteria

Inclusion Criteria

  • •temporal lobe medically refractory epilepsy patients with hippocampal atrophy

Exclusion Criteria

  • •under 18 or over 65 years old patients
  • •previous neurological surgery
  • •other neurodegenerative diseases

Outcomes

Primary Outcomes

seizure frequency

Time Frame: 6 months

Secondary Outcomes

  • adverse effects(6 months)
  • hippocampal volume(6 months)
  • cognitive performance(6 months)

Study Sites (1)

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