Transposition of the Mini-Mental State in Sign Language
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 195
- 试验地点
- 8
- 主要终点
- Assessment of internal consistency of MMS-LS test for the diagnosis of cognitive impairment among deaf patients by a correlation analysis followed by Cronbach's alpha test
研究概览
简要总结
In France the prevalence of pre-lingual deafness is between 1 and 1.4 per 1000 habitants, and according to very conservative estimates, about 44 000 deaf persons use the sign language. Additionally, the prevalence of dementia in France is close to 1% (850 000 dements for a total population of 65 millions). The prevalence of dementia in pre-lingual deaf adults has also been described and is between 1 and 1.4 /100 000 habitants.
The Mini Mental State Examination (MMSE) of Folstein is a test recommended to perform the cognitive evaluation for the detection of mental disorders including dementia, and a consensual French version exists prepared by GRECO (Group of Research and Cognitive Assessments). However, to date, there are no simple, rapid and validated screening tests to study cognitive disorders in deaf persons who use the sign language. The only tests available allow a late diagnosis avoiding an optimal treatment of the patients.
详细描述
The objective of this study is to assess the intrinsic quality of the tool MMS-LS, a mini-mental state examination that has been adapted to the sign language in order to monitor cognitive disorders in deaf people who speak sign language.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults> 18 years
- •Pre-lingual deafness
- •Use of French sign language
排除标准
- •Refusal to sign the consent
- •Severe visual impairment with lower acuity (less than 0.5)
- •Severe motor difficulties impeding the practice of sign language
研究组 & 干预措施
deaf persons with potential dementia
干预措施: application of the mini-mental state test (Behavioral)
结局指标
主要结局
Assessment of internal consistency of MMS-LS test for the diagnosis of cognitive impairment among deaf patients by a correlation analysis followed by Cronbach's alpha test
时间窗: At baseline, 1 year and 2 years follow-up visits
次要结局
- Diagnostic performance and predictive values of MMS-LS test for acquired dementia.(Baseline, 1 year and 2 years follow-up visits)
- Diagnostic performance and predictive values of MMS-LS test for suspected dementia.(Baseline, 1 year and 2 years follow-up visits)
- Description of MMS-LS test results(Baseline)
- Correlation between MMS-LS score and CDR level(Baseline, 1 year and 2 years follow-up visits)