The Effect of N-Acetyl cysteine on Cognitive performance Impairment
Phase 3
Recruiting
- Conditions
- Bipolar.Bipolar disorder
- Registration Number
- IRCT20220516054879N7
- Lead Sponsor
- Rasht University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 52
Inclusion Criteria
Patients with bipolar disorder older than 18 years
Treatment with electroconvulsive therapy
Exclusion Criteria
Schizophrenia
Drug Abusers
Psychiatric diseases with other mental illnesses
Bradyarrhythmia
Liver or kidney failure
History of seizures
Drug or alcohol use
History of asthma or bronchospasm
History of allergy to n-acetyl cycteine
Pregnancy
Breastfeeding
Currently uncontrolled hypertension
Active peptic ulcer
Receiving nitroglycerin
History of severe skin disease such as Steven Johnson
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cognitive impairment. Timepoint: Before intervention and two weeks after beginning of the intervention. Method of measurement: Mini-Mental State Examination questionnaire.
- Secondary Outcome Measures
Name Time Method Systolic blood pressure. Timepoint: Before the intervention and two weeks after beginning of the intervention. Method of measurement: Digital blood pressure measurement device.;Diastolic blood pressure. Timepoint: Before the intervention and two weeks after beginning of the intervention. Method of measurement: Digital blood pressure measurement device.