The effects of post-conditioning and administration of Vitamin C on intramuscular high energy phosphate levels

niversitätsklinik für klinische Pharmakologie, Medizinische Universität Wien0 个研究点开始时间: 2007年5月23日最近更新: 2012年3月19日

试验速览

暂无简介。

•-Men aged between 18 and 45 years
•-Nonsmoker for more than 3 months
•-Body mass index between 18 and 25 kg/m2
•-Normal findings in medical history and physical examination unless the investigator considers an abnormality to be clinically irrelevant
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) no
•F.1.3.1 Number of subjects for this age range

•Any of the following will exclude a subject from the study:
•-Regular use of medication, abuse of alcoholic beverages, participation in a clinical trial in the 3 weeks preciding the study
•-Evidence of hypertension, pathologic hyperglycemia, hyperlipidemia
•-Treatment in the previous 3 weeks with any drug including over-the-counter drugs.
•-Symptoms of a clinically relevant illness in the 2 weeks before the first study day
•-History or presence of gastrointestinal, liver of kidney disease, or other conditions known to interfere with distribution, metabolism or excretion of the study drug
•-Blood donation during the previous 3 weeks
•-History of hypersensitivity to parenteral vitamin C.
•-Glucose-6-phosphate dehydrogenase deficiency
•-Thalassemia, haemochromatosis
•-History of urolithiasis
•-Any magnetic or paramagnetic device not removable
•-Claustrophobia
•-Regular use of supplementary oral Vitamin C or Vitamin C containing substances

发起方

niversitätsklinik für klinische Pharmakologie, Medizinische Universität Wien