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Clinical Trials/NCT07601919
NCT07601919CompletedNot Applicable

Comparison of Outcome of Emergency Laparotomy Wound Closed by Interrupted Suturing Versus Continuous Suturing.

Muhammad Aamir Latif1 site in 1 country184 target enrollmentStarted: August 15, 2025Last updated:

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Enrollment
184
Locations
1

Study Overview

Brief Summary

Emergency laparotomy is associated with high morbidity, particularly due to wound dehiscence and infection. Choosing an optimal suturing technique can significantly impact patient outcomes, but data on the comparison of interrupted suturing with continuous suturing in emergency settings is limited. Therefore, the current study was planned, aiming to compare the outcome of emergency laparotomy wounds closed by interrupted suturing versus continuous suturing.

Detailed Description

Interrupted suturing has been suggested to provide better tensile strength and allow for better healing by reducing tension across the wound. Several studies have reported a significantly lower incidence of wound dehiscence with interrupted suturing compared to continuous suturing. Additionally, interrupted suturing may lower the risk of wound infection by reducing bacterial migration along the suture line. Despite that, continuous suturing generally provides faster, more cost-effective wound closure with superior cosmetic outcomes and reduced short-term pain compared to interrupted sutures. If the study finds interrupted suturing to have superior outcomes, it could become the preferred method for emergency laparotomy closure, improving surgical success rates and patient recovery.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
18 Years to 60 Years (Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Patients of either gender
  • Aged 18-60 years
  • Undergoing emergency laparotomy

Exclusion Criteria

  • Unfit for surgery
  • History of diabetes
  • Immuno-compromised
  • Pregnant/lactating mothers
  • Malignancy
  • Very low or very high body mass index (< 15kg/m2 or > 30kg/m2)

Investigators

Sponsor
Muhammad Aamir Latif
Sponsor Class
Other
Responsible Party
Sponsor Investigator
Principal Investigator

Muhammad Aamir Latif

Research Consultant

RESnTEC, Institute of Research

Study Sites (1)

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