How physical training is able to improve chest pain in patients without coronary disease

Phase 4

Completed

• Conditions: Angina Microvascular; Coronary Artery Disease; Scintigraphy; Myocardial Perfusion Image.; C14.280.647.187.575; C14.280.647.250.260; E01.370.350.710; E01.370.350.130.875

• Registration Number: RBR-9p4kst
• Lead Sponsor: Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-06-17
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Data analysis completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Patients with a diagnosis of coronary microvascular angina.
Patients of both genders, aged between 18 and 80 years.

Exclusion Criteria

Precordial pain whose clinical features suggest non-ischemic origin;
Presence of obstructive lesions in coronary arteries that irrigate the ischemic area;
Physical limitation to aerobic exercise on treadmill;
Contraindication to the practice of moderate intensity aerobic physical activity.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Whether physical training would be able to reduce the patient's anginal frame. Evaluated by the quality of life questionnaire.<br>;Whether physical training would be able to reduce myocardial perfusion defects. Evaluated by myocardial perfusion scintigraphy.

Secondary Outcome Measures

Name	Time	Method
Whether the improvement in the anginal condition would be associated with an improvement in the quality of life. Evaluated by the quality of life questionnaire.<br>;Whether physical training would increase the patients' physical capacity. Evaluated by cardiopulmonary test.;What mechanisms would be involved in improving myocardial perfusion. Evaluated by endothelial function and autonomic control.