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Influence of breast milk versus formula milk on the time the ductus arteriosus closes in preterm infants

Not Applicable
Conditions
Q25.0
Patent ductus arteriosus
Registration Number
DRKS00019919
Lead Sponsor
Klinikum der Universität München, Dr. von Haunersches Kinderspital; Neonatologie
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
49
Inclusion Criteria

28 0/7 - 31 6/7 wks gestation

Exclusion Criteria

• SGA < 3. centile
• medically / surgically closed PDA
• congenital problems of the GI-tract
• congenital heart defect,
• asphyxia

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Gut perfusion determined by ultrasound doppler blood-flow velocity in cm/s in the mesenteric superior artery on postnatal days 1,3,5,7 and at discharge<br><br>
Secondary Outcome Measures
NameTimeMethod
Progress of PDA-closure (Day of closure by ECHO-cardiographie)<br><br>Near infrared Spectroskopie (NIRS) of right lower abdomen (% Oxygen saturation) at postnatal days 1,3,5,7 and at discharge.<br><br>Body composition determined by Peapod at at postnatal days 1,3,5,7 and at discharge, if possible on clinical assessment
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