NL-OMON27745
Completed
Not Applicable
BONDS: Boosting Oxytocin after trauma: Neurobiology and the Development of Stress-related psychopathology .
ConditionsPTSD, trauma-related psychopathology
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- PTSD, trauma-related psychopathology
- Sponsor
- Academic Medical Center - University of Amsterdam
- Enrollment
- 220
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
Olff, M., W. Langeland, A. Witteveen, D. Denys, 2010. A psychobiological rationale for oxytocin in the treatment of posttraumatic stress disorder. CNS spectr., v. 15, no. 8, p. 522-30.
Frijling, J. L., van Zuiden, M., Koch, S. B., Nawijn, L., Goslings, J. C., Luitse, J. S., ... & Olff, M. (2014). Efficacy of oxytocin administration early after psychotrauma in preventing the development of PTSD: study protocol of a randomized controlled trial. BMC psychiatry, 14(1), 92.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Presentation at the Trauma Unit or Emergency Department after a potentially traumatic event, according to PTSD A1 criterion in the DSM\-IV;
- •2\. Trauma Screening Questionnaire (TSQ) ≥ 5, or Peritraumatic Distress Inventory (PDI) ≥ 17 between 24 and 72 hours after trauma exposure;
Exclusion Criteria
- •1\. Any severe or chronic systemic disease;
- •2\. Current psychotic, bipolar, substance\-related, severe personality disorder, or mental retardation;
Outcomes
Primary Outcomes
Not specified
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