One Week of Magnesium Supplementation Lowers IL-6, Perceived Pain and Increases Post Exercise Blood Glucose in Response to Downhill Running
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 9
- 试验地点
- 2
- 主要终点
- 24 hr post exercise maximal force testing of the dominant leg on the isokinetic dynamometer
研究概览
简要总结
This study investigated the effect of magnesium supplementation on exercise performance and functional recovery in recreational endurance athletes in conjunction with measures of blood glucose, lactate, IL-6 and sIL-6R.
详细描述
Magnesium status can directly affect circulating glucose concentrations both during and post exercise. In addition, magnesium supplementation has been shown to reduce circulating IL-6 concentrations post exercise in humans. It is conceivable that such observations are linked through the role of IL-6 in glucose regulation, possibly in combination with sIL-6R. Together, magnesium intake may have the potential to effect exercise performance and recovery through glucose availability. This in turn may be connected to the production of IL-6 and sIL-6R which have been established to influence exercise fatigue and perception of pain (muscle soreness).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 20 Years 至 35 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Regular recreational runner, running around 3 times per week
- •Capable of running 10 km in ~ 40 minutes.
排除标准
- •Any signs or symptoms of cardiovascular issues.
- •Any recent form of injury or illness.
- •Currently, or in the last 3 months, have consumed multivitamin supplements
- •Currently, or in the last 3 months, have consumed anti-inflammatory medications.
结局指标
主要结局
24 hr post exercise maximal force testing of the dominant leg on the isokinetic dynamometer
时间窗: 1 day
Maximal force produced from the dominant leg (eccentric and concentric) on an isokinetic dynamometer.
Downhill 10 km treadmill time trial performance
时间窗: 1 day
Maximal 10 km time trial performance on a treadmill
次要结局
- Interleukin-6(up to 2 days)
- Lactate(up to 2 days)
- Glucose(up to 2 days)
- Perceived muscle soreness(up to 4 days)
- Creatine kinase(up to 2 days)
- Soluble interleukin-6 receptor(up to 2 days)
研究者
Charles Steward
Lecturer
University of Worcester