Impact of Mitral Valve Annuloplasty on the Tricuspid Valve Complex
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Tricuspid (Valve); Deformity
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
- Enrollment
- 22
- Primary Endpoint
- Postoperative geometric changes in tricuspid valve annulus (TA)
- Status
- Terminated
- Last Updated
- 7 years ago
Overview
Brief Summary
The purpose of this study is to evaluate the impact of isolated mitral valve annuloplasty on the geometry and the function of the tricuspid valve complex.
Detailed Description
The proposed pathogenesis of functional tricuspid regurgitation (TR) in mitral valve disease seems incomplete. Because both atrioventricular valves are closely connected to each other by means of the cardiac fibrous skeleton, the geometry of the tricuspid valve is likely to be distorted after ring-annuloplasty of the mitral valve. This could lead to the development of functional TR, or to an increase in TR severity. To test this hypothesis, a prospective study will be started in patients undergoing isolated mitral valve annuloplasty.
Investigators
Eligibility Criteria
Inclusion Criteria
- •all patients 18 years of age or older undergoing minimally invasive, isolated mitral valve annuloplasty
Exclusion Criteria
- •concomitant tricuspid valve surgery
- •atrial fibrillation at the moment of surgery
- •poor echocardiographic windows
Outcomes
Primary Outcomes
Postoperative geometric changes in tricuspid valve annulus (TA)
Time Frame: day 0
Measurement of changes in 3D descriptors of the TA (e.g. changes from baseline in the TA area of the best-fit plane in cm\^2, and changes from baseline in the height of each TA point to the TA best-fit plane in mm)