Aronia and Cognitive Fitness: Focus on Brain Insulin-Sensitivity and Vascular Functio

Completed

• Conditions: cognitief functioneren; cognition

• Registration Number: NL-OMON55924
• Lead Sponsor: niversiteit Maastricht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

men and women, age 55-75, BMI 25-35 kg/m2

Exclusion Criteria

smoking, diabetes mellitus, active cardiovascular disease, severe medical
conditions, use of supplements or medication affecting main outcomes,
contra-indications for MRI

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Cerebral blood flow responses before and after intranasal insulin<br /><br>administration will be non-invasively quantified by MRI. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Furthermore, effects of AME on cognitive performance will be assessed.<br /><br>Exploratory outcomes are other potential mechanisms responsible for observed<br /><br>effects on cognitive function, and other perceivable benefits such as vascular<br /><br>improvements and metabolic markers.</p><br>