The use of a food for special medical purposes (product ID 4804/4805) in patients with early Alzheimer’s Disease.A randomised, controlled, double-blind 12-week study on cognitive performance, with a 12-week extension.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 214
研究概览
简要总结
Efficacy of a medical food in mild Alzheimer’s disease: A randomized, controlled trial. Alzheimer’s & Dementia 6 (2010) 1–10.
Philip Scheltensa,*, Patrick J. G. H. Kamphuisb, Frans R. J. Verheyc, Marcel G. M. Olde Rikkertd, Richard J. Wurtmane, David Wilkinsonf, Jos W. R. Twiskg, Alexander Kurzh.
EFFICACY OF A MEDICAL FOOD ON COGNITION IN ALZHEIMER’S DISEASE: RESULTS FROM SECONDARY ANALYSES OF A RANDOMIZED, CONTROLLED TRIAL. J Nutr Health Aging. 2011 15(8):720-4
P.J.G.H. KAMPHUIS, F.R.J. VERHEY, M.G.M. OLDE RIKKERT, J.W.R. TWISK, S.H.N. SWINKELS, P. SCHELTENS
Effect of a medical food on Body Mass Index and activities of daily living in patients with Alzheimer’s disease: secondary analyses from a randomized, controlled trial. J Nutr Health Aging. 2011 15(8), 672-676.
P.J.G.H. kamphuis, F.R.J. verhey, M.G.M. Olde Rikkert, J.W.R. Twisk, S.H.N. Swinkels, P. Scheltens.
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. Out-patients, age >= 50 yrs;
- •2. Diagnosis of probable Alzheimer Disease according to the NINCDS-ADRDA criteria;
排除标准
- •1. Vascular dementia;
- •2. History, or expected need during the study of cholinesterase-inhibitors or NMDA-receptor antagonists or medications with cholinergic or anticholinergic side effects;