A Multi-Dose Study With a Treatment for Open-Angle Glaucoma

Phase 2

Withdrawn

• Conditions: Open-Angle Glaucoma
• Interventions: Drug: Placebo; Drug: Anecortave Acetate

• Registration Number: NCT00705770
• Lead Sponsor: Alcon Research

Brief Summary

The purpose of this study is to determine whether Anecortave Acetate is effective for lowering intraocular pressure caused by open-angle glaucoma.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-05
• Study First Submitted: 2008-06-24
• Study First Submitted QC: 2008-06-25
• Study First Posted: 2008-06-26
• Status Verified: 2008-07
• Primary Completion: 2008-07
• Study Completion: 2008-07
• Last Update Submitted: 2012-05-29
• Last Update Posted: 2012-05-30

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Patients at least 18 years old with a clinical diagnosis of Open-Angle Glaucoma for at least 6 months and currently treated with a monotherapy hypotensive medication

Exclusion Criteria

• Prior angle surgery in the study eye, severe visual field loss in either eye, and any other form of glaucoma besides open-angle glaucoma

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1	Placebo	Placebo treatment with vehicle
4	Anecortave Acetate	High dose of study medication
2	Anecortave Acetate	Low dose of study medication
3	Anecortave Acetate	Middle dose of study medication

Primary Outcome Measures

Name	Time	Method
Mean Intraocular Pressure	6 months

Secondary Outcome Measures

Name	Time	Method
Percent of patients with therapeutic benefit, number and percent of treatment failure and time to treatment failure	6 months