MPAC-study: A feasibility study of the co-registration of MRI-imaging with PAthological assessment of primary tumor extension in patients with uterine Cervical tumors.

Completed

• Conditions: cervical cancer; uterine cervical carcinoma; 10038594

• Registration Number: NL-OMON37645
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Trial is onging in other countries

Detailed Description

Not available

Study Timeline

• Study Completion: 2017-01-24
• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 15

Inclusion Criteria

Patients with a carcinoma of the cervix for whom a Wertheim surgical procedure is planned. They must be older than 18 years of age and have a WHO status of 0 or 1.

Exclusion Criteria

Exclusioncirteria are MRI related. Patients with claustrophobia, a pacemaker, medicine pump, neurostimulator, cochlear implants, other metal implants in the pelvis wich would disturb the image. In some cases surgical clips in the brain are contra-indicated, this will be evaluated conform standard protocol. Patients with a GFR < 30 ml/min/1,73 m² wil be excluded.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The feasibility of co-registration of the microscopic images of the surgical<br /><br>specimen into the T2 MRI images will be evaluated. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The secondary endpoint of the study is the correlation of the tumor extend in<br /><br>uterus and parametria on MRI and microscopic images. </p><br>