se of Kiratatikta and Guduchi in Sickling

Phase 2

• Conditions: Health Condition 1: D571- Sickle-cell disease without crisis

• Registration Number: CTRI/2022/01/039669
• Lead Sponsor: Dr CP Sinha

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 February 2022

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

i)Patients will be selected on the basis of sign and symptoms of sickle cell anaemia group:-

1.Anaemia

2.Jaundice

3.Bodyache (pain & crisis)

4.Abdominal colic

5.Palpitation

6.Hand foot syndrome

7.Loss of appetite

8.Sternal pain

9.Pyrexia

10. Hepatomegaly

11. Splenomegaly

12. Repeated blood transfusion

13. Repeated respiratory infections

14. Pain in Hip region

ii) Hemoglobin more than 6gm/dl.

iii) Age group between 5 Years to 50Years.

As per the above sign and symptoms patients examination Performa will be prepared and patients will be selected for clinical trial.

Exclusion Criteria

1.Patients who are suffering from pain and other symptoms other then Sickle cell anaemia will be excluded from the clinical trial.

2.The patients who are below 5 years and above 50 years.

3.Pregnancy and lactations

4.Severe illness like Tuberculosis, Cancer, Cirrhosis of liver, aplastic anaemia etc. also be excluded.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
aboratory Investigation will be assess:- <br/ ><br>1.Haematological investigations (CBC, Vit.B12, Vit.D) <br/ ><br>2.Biochemical investigations( LFT, KFT, Lipid profile) <br/ ><br>3.Hb electrophoresis <br/ ><br>4.Urine test (routine and microscopic along with bile salt and bile pigment) <br/ ><br>5.Radiological investigations ( if required) <br/ ><br>6.Invitro slide study <br/ ><br>Timepoint: 2 months

Secondary Outcome Measures

Name	Time	Method
aboratory Investigation will be assess:- <br/ ><br>1.Haematological investigations (CBC, Vit.B12, Vit.D) <br/ ><br>2.Biochemical investigations( LFT, KFT, Lipid profile) <br/ ><br>3.Hb electrophoresis <br/ ><br>4.Urine test (routine and microscopic along with bile salt and bile pigment) <br/ ><br>5.Radiological investigations ( if required) <br/ ><br>6.Invitro slide study <br/ ><br>Timepoint: at 15 days, 30 days, 45 days and 60 days.