Clinical Evaluation of Khadirastaka Kvatha and Local Application of Manjisthadi Taila in the Management of Psoriasis
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- To observe and find out changes in signs and symptoms of the psoriasis after the oral administration of khadirastaka kwatha and local application of manjisthadi taila.
研究概览
简要总结
Psoriasis is a complex, chronic, multifactorial, inflammatory disease that involves hyper proliferation of keratinocytes in the epidermis, with an increase in the epidermal cell turnover rate. 20 patients of psoriasis who fulfill the inclusion criteria were selected from OPD and gave them oral administration of khadirastak kwatha 40 ml twice a day and manjisthadi taila for local application twice a day. Patients were treated for 8 weeks and assessed before and after the treatment. It shows significant effect in all symptoms as well as PASI and DLQI.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •patients will be diagnosed with psoriasis with the help of presence of signs and symptoms like scaling(dalana),itching(kandu),erythema (krusna aruna varna),loss of perspiration (asvedanam),dryness(rukshta),auspitz sign,candle grease sign,koebners phenomenon.
排除标准
- •1.Pregnant or lactating females.
- •2.Patients who have taken medicine of corticosteroid drugs or immune-suppressants or other biological medicines within last 6 months.
- •3.Known case of diseases like AIDS, STD, TB, heart diseases and other disorders which lead to fetal condition for the patients.
- •4.Patients having diabetes mellitus.
- •5.Other concomitant skin disease occurring with allergic reaction of any other disease.
结局指标
主要结局
To observe and find out changes in signs and symptoms of the psoriasis after the oral administration of khadirastaka kwatha and local application of manjisthadi taila.
时间窗: 2 weeks
次要结局
- 1.To evaluate the changes in PASI index in the patients of psoriasis.(2.To find out the improvement in quality of life through changes in DLQI in the patients of psoriasis.)
研究者
Dr Feni R Patel
J.S.Ayurved Mahavidyalay