The Effects of High-Flow Nasal Oxygen Therapy on Respiratory Complications and Post-Procedural Recovery Time in Patients Undergoing Sedated EBUS-TBNA
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Respiratory Complications
研究概览
简要总结
This study aims to evaluate the effects of high-flow nasal oxygen therapy on respiratory complications, blood gas parameters, and post-procedural recovery in patients undergoing sedated endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). Participants will be assigned to receive either high-flow nasal oxygen therapy or conventional oxygen therapy during the procedure. The incidence of respiratory complications, blood gas changes, and recovery outcomes will be compared between the two groups.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥18 years. Scheduled to undergo sedated EBUS-TBNA. Ability to provide written informed consent. ASA physical status I-III.
排除标准
- •Age <18 years.
- •Pregnancy.
- •Requirement for endotracheal intubation or general anesthesia.
- •Severe hemodynamic instability.
- •Refusal to participate in the study.
- •Contraindication to high-flow nasal oxygen therapy.
研究组 & 干预措施
Group H (High-Flow Nasal Oxygen Group)
Patients undergoing sedated EBUS-TBNA who receive high-flow nasal oxygen therapy during the procedure. Respiratory complications, oxygenation parameters, blood gas values, and post-procedural recovery outcomes are evaluated.
干预措施: High-Flow Nasal Oxygen Therapy (Device)
Group C (Conventional Oxygen Group)
Patients undergoing sedated EBUS-TBNA who receive conventional oxygen therapy during the procedure. Respiratory complications, oxygenation parameters, blood gas values, and post-procedural recovery outcomes are evaluated.
干预措施: Conventional Oxygen Therapy (Device)
结局指标
主要结局
Respiratory Complications
时间窗: During the procedure
Incidence of respiratory complications during sedated EBUS-TBNA, including hypoxemia, oxygen desaturation, apnea, airway obstruction, and the need for airway interventions.
次要结局
- Oxygen partial pressure (PaO2)(Baseline and within 15 minutes after completion of the endobronchial Ultrasound-Transbronchial Needle Aspiration (EBUS-TBNA) procedure)
- Carbon dioxide partial pressure (PvCO2)(Baseline and within 15 minutes after completion of the EBUS-TBNA)
- Venous pH(Baseline and within 15 minutes after completion of the EBUS-TBNA procedure.)
- Venous Oxygen Saturation (SvO2)(Baseline and within 15 minutes after completion of the EBUS-TBNA procedure.)
- Recovry Time(Up to 2 hours post-procedure)
研究者
Özlem Kapusuz
Anesthesiology and Reanimation Specialist
Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital