Incidence of Descemet Membrane Detachment Post GATT by AS OCT

Not Applicable

Active, not recruiting

• Conditions: Angle Glaucoma Open
• Interventions: Procedure: Gonioscopy-Assisted Transluminal Trabeculotomy

• Registration Number: NCT05932940
• Lead Sponsor: Cairo University

Brief Summary

detection of Incidence of Descemet membrane detachment post gonioscopy-assisted transluminal trabeculotomy by anterior segment optical coherence tomography in patients with open angle glaucoma.

Detailed Description

In our study, which should include 30 eyes with OAG who underwent 360 GATT Screening for Descemet Membrane Detachment will be done by Anterior Segment Optical coherence Tomography using SD-OCT: Optovue RTVue (Optovue Inc., Fremont, CA, USA) for the angle day 1 post operative for all patients and 1 week post operative in cases with Descemet membrane detachment to check for spontaneous resolution.

One month post-operative the patients underwent

* Best corrected visual acuity (BCVA) using decimal.

* IOP measurement using GAT.

Study Timeline

• Study Start: 2022-12-01
• Study First Submitted: 2023-05-07
• Study First Submitted QC: 2023-07-03
• Study First Posted: 2023-07-06
• Status Verified: 2024-03
• Primary Completion: 2024-03-01
• Last Update Submitted: 2024-03-13
• Last Update Posted: 2024-03-15
• Study Completion: 2024-05-10

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1. Age 18 - 70 years.
2. Patients with open angle glaucoma undergoing gonioscopy assisted transluminal trabeculotomy.

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Exclusion Criteria

1. Patients with with open angle glaucoma and aphakia.
2. Patients with Congenital Glaucoma.
3. Patients with open angle glaucoma undergoing phaco -gonioscopy-assisted transluminal trabeculotomy.
4. Patients with neovascular glaucoma.
5. Patients with pigmentary Glaucoma.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
GATT group	Gonioscopy-Assisted Transluminal Trabeculotomy	detection of incidence of Descemet membrane detachment post gonioscopy-assisted transluminal trabeculotomy by anterior segment optical coherence tomography in patients with open angle glaucoma.

Primary Outcome Measures

Name	Time	Method
Incidence of Descemet Membrane detachment post GATT	4 months	Incidence of Descemet membrane Detachment post Gonioscopy-Assisted Transluminal Trabeculotomy

Secondary Outcome Measures

Name	Time	Method
Amount of reduction of IOP and Glaucoma NGM	4 months	Amount of reduction of intraocular pressure and Number of Glaucoma medications
Incidence of Hyphema post GATT	4 months	Incidence of Hyphema post Gonioscopy-Assisted Transluminal Trabeculotomy
Incidence of Descemet membrane detachment post gonioscopy-assisted transluminal trabeculotomy by anterior segment optical coherence tomography in patients with open angle glaucoma.	4 months	Incidence of Descemet membrane detachment post gonioscopy-assisted transluminal trabeculotomy by anterior segment optical coherence tomography in patients with open angle glaucoma.

Trial Locations

Locations (1)

Facility of medicine , Cairo University; 🇪🇬 Cairo, Almanial, Egypt