Investigation of the usefulness of pulmonary oxygen consumption determined from indirect calorimetry and hemodynamic parameters in the evaluation of severe respiratory disease
Not Applicable
Recruiting
- Conditions
- Patients undergoing mechanical ventilation with tracheal intubation in the ICU due to severe respiratory disease
- Registration Number
- JPRN-UMIN000051665
- Lead Sponsor
- Fukushima Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 43
Inclusion Criteria
Not provided
Exclusion Criteria
Exclude patients and timings with any of the following: 1) Timing of using extracorporeal circulation 2) Patients with an arteriovenous shunt 3) Timing within 10 minutes after changing ventilator settings 4) Cardiogenic pulmonary edema is determined to be the main cause of worsening respiratory status, or patients undergoing blood gas analysis from a CV catheter to evaluate respiratory status.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method In this study, we mainly examine three items: 1) the relationship between mortality and delta VO2, 2) the relationship between delta VO2 and the P/F ratio 3) the relationship between changes in delta VO2 (delta-delta VO2) and changes in the P/F ratio (delta P/F).
- Secondary Outcome Measures
Name Time Method # Relationship between delta VO2, ScvO2, and O2 extraction rate (O2ER) # Relationship between delta VO2 and CRP # Relationship between delta VO2 and days of mechanical ventilation, length of stay in ICU, reintubation rate, SBT success/failure rate, and RSBI (SBT: Spontaneous breathing trial, RSRI: Rapid Shallow Breathing Index)