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Clinical Trials/NCT06223087
NCT06223087
Active, not recruiting
Not Applicable

Effects of Winter Swimming on Blood Morphological, Rheological, and Biochemical Indicators and Oxidative Stress in Males

University School of Physical Education, Krakow, Poland1 site in 1 country30 target enrollmentStarted: January 1, 2021Last updated:
ConditionsCold Exposure

Overview

Phase
Not Applicable
Status
Active, not recruiting
Sponsor
University School of Physical Education, Krakow, Poland
Enrollment
30
Locations
1
Primary Endpoint
blood sampling: haemoglobin mass

Overview

Brief Summary

Exposure of the human body to cold water triggers numerous beneficial physiological changes. The study aimed to assess the impact of regular winter swimming on blood morphological, rheological, and biochemical indicators and activity of antioxidant enzymes in males. The study includes winter swimmers and a control group. Blood samples were taken twice - before the start (November) of the winter swimming season and after its end (March). The average duration of ice water baths was 3-5 minutes, with a minimum frequency of once a week. The water temperature during the swimming did not exceed 10°C, approaching 0°C during the winter period.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Eligibility Criteria

Ages
25 Years to 60 Years (Adult)
Sex
Male
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Good health, practitioners of winter swimming
  • control group: never did winter swimming and had a sedentary lifestyle.

Exclusion Criteria

  • medical contraindications to winter bathing

Outcomes

Primary Outcomes

blood sampling: haemoglobin mass

Time Frame: twice: before the start of cold swimming in November and 5 months later (March), after the end of winter swimming

Determination of: mean corpuscular haemoglobin (MCH) \[pg\],

blood sampling: Erythrocytes

Time Frame: twice: before the start of cold swimming in November and 5 months later (March), after the end of winter swimming

Determination of mean corpuscular volume (MCV) \[fl\], red blood cell distribution width standard deviation (RDW-SD) \[fl\],

blood sampling: haemoglobin

Time Frame: twice: before the start of cold swimming in November and 5 months later (March), after the end of winter swimming

Determination of: Haemoglobin \[g/dl\], mean corpuscular haemoglobin concentration (MCHC) \[g/dl\],

blood sampling: erythrocytes

Time Frame: twice: before the start of cold swimming in November and 5 months later (March), after the end of winter swimming

Measurement of: Erythrocytes \[mln/μl\],

blood sampling: haematocrit

Time Frame: twice: before the start of cold swimming in November and 5 months later (March), after the end of winter swimming

Determination of: haematocrit \[%\], red blood cell distribution width coefficient of variation (RDW-CV) \[%\],

blood sampling: rheology part 1

Time Frame: twice: before the start of cold swimming in November and 5 months later (March), after the end of winter swimming

Determination of red cell elongation index (EI) \[arbitrary unit: AU\], erythrocyte aggregation amplitude (AMP) \[AU\],

blood sampling: rheology part 2

Time Frame: twice: before the start of cold swimming in November and 5 months later (March), after the end of winter swimming

Determination of: aggregation index (AI) \[%\],

blood sampling:rheology part 3

Time Frame: twice: before the start of cold swimming in November and 5 months later (March), after the end of winter swimming

Determination of: half-time of total aggregation (t1/2) \[s\].

blood sampling: platelets and leukocytes

Time Frame: twice: before the start of cold swimming in November and 5 months later (March), after the end of winter swimming

Measurements of: Platelets \[thousands/μl\], Leukocytes \[thousands/μl\], Neutrophils \[thousands/μl\], Eosinophils \[thousands/μl\], Basophils \[thousands/μl\], Lymphocytes \[thousands/μl\], Monocytes \[thousands/μl\].

blood sampling: oxidative stress - superoxide dismutase

Time Frame: twice: before the start of cold swimming in November and 5 months later (March), after the end of winter swimming

Measurement of superoxide dismutase (SOD) \[U/ml\],

blood sampling: Testosterone

Time Frame: twice: before the start of cold swimming in November and 5 months later (March), after the end of winter swimming

Determination of Testosterone concentration \[ng/dl\],

blood sampling: Cortisol

Time Frame: twice: before the start of cold swimming in November and 5 months later (March), after the end of winter swimming

Determination of Cortisol concentration \[µg/dl\],

blood biochemistry: Creatine

Time Frame: twice: before the start of cold swimming in November and 5 months later (March), after the end of winter swimming

Determination of Creatinine concentration \[µmol/l\],

blood sampling: oxidative stress

Time Frame: twice: before the start of cold swimming in November and 5 months later (March), after the end of winter swimming

Measurement of catalase (CAT) \[nmol/min/ml\], and glutathione peroxidase (GPx) \[nmol/min/ml\].

blood biochemistry: Urea

Time Frame: twice: before the start of cold swimming in November and 5 months later (March), after the end of winter swimming

Measurement of: Urea \[mmol/l\].

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
University School of Physical Education, Krakow, Poland
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Aneta Teleglow

Head of Blood Physiology Laboratory

University School of Physical Education, Krakow, Poland

Study Sites (1)

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