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Evaluation of cumulative steroid doses in adult nephrotic syndrome

Not Applicable
Not yet recruiting
Conditions
Health Condition 1: N00-N99- Diseases of the genitourinary system
Registration Number
CTRI/2021/04/033110
Lead Sponsor
Funding applied for
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Not Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Adult (>=18 years) patients with NS due to primary MCD/FSGS who achieved remission (SSNS) when treated for the first time with oral prednisolone 1mg/kg/day for at-least 4 weeks and a maximum duration of 16 weeks.

Exclusion Criteria

1) eGFR <60ml/min per 1.73 m2

(2) Nephrotic range proteinuria without nephrotic syndrome

(3) Presence of other concomitant diseases on kidney biopsy

(4) Secondary cause of MCD and FSGS

(5) Concomitant systemic disease like diabetes, hepatitis B or C or HIV infection

(6) Prior treatment with immunosuppression for NS

(7) Prior treatment with immunosuppression for any other indication in the past 6 months

(8) Patients who have concomitantly received other immunosuppressive drugs in addition to prednisolone for initial treatment of the NS

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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