ACTRN12611000146998
Recruiting
未知
Predictors of Response to Therapy in New-Presentation Idiopathic Dilated Cardiomyopathy
Professor Joseph Selvanayagam0 sites200 target enrollmentFebruary 8, 2011
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Idiopathic Dilated Cardiomyopathy
- Sponsor
- Professor Joseph Selvanayagam
- Enrollment
- 200
- Status
- Recruiting
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Clinical heart failure (New York Heart Association class II \- IV) on first presentation, LV ejection fraction \<45% as measured by echocardiography, ventriculography, or cardiac
- •scintigraphy
Exclusion Criteria
- •Standard MRI contraindications, including permanent pacemaker, implantable defibrillator,
- •severe claustrophobia, Significant coronary artery disease, as manifest by \>70% stenosis in a major epicardial
- •coronary artery or the presence of a moderate or greater zone of ischaemia/infarction on
- •stress imaging, Concomitant valvular heart disease as a cause or central contributor to the heart failure
- •(excluding functional mitral regurgitation, Hypertrophic obstructive cardiomyopathy, Myocarditis, amyloidosis, sarcoidosis, uncontrolled thyroid disease, post\-partum
- •cardiomyopathy, Renal impairment (eGFR \<60ml/min) will be an exclusion criterion from the administration
- •of gadolinium, New York Heart Association class IV symptoms (i.e. dyspnoea at rest), and unstable
- •ischaemic heart disease will be exclusion criteria from cardiopulmonary exercise testing
Outcomes
Primary Outcomes
Not specified
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