ACTRN12611000146998招募中未知
Predictors of Response to Therapy in New-Presentation Idiopathic Dilated Cardiomyopathy
Professor Joseph Selvanayagam0 个研究点目标入组 200 人开始时间: 2011年2月8日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 发起方
- 入组人数
- 200
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •Clinical heart failure (New York Heart Association class II - IV) on first presentation, LV ejection fraction <45% as measured by echocardiography, ventriculography, or cardiac
- •scintigraphy
排除标准
- •Standard MRI contraindications, including permanent pacemaker, implantable defibrillator,
- •severe claustrophobia, Significant coronary artery disease, as manifest by >70% stenosis in a major epicardial
- •coronary artery or the presence of a moderate or greater zone of ischaemia/infarction on
- •stress imaging, Concomitant valvular heart disease as a cause or central contributor to the heart failure
- •(excluding functional mitral regurgitation, Hypertrophic obstructive cardiomyopathy, Myocarditis, amyloidosis, sarcoidosis, uncontrolled thyroid disease, post-partum
- •cardiomyopathy, Renal impairment (eGFR <60ml/min) will be an exclusion criterion from the administration
- •of gadolinium, New York Heart Association class IV symptoms (i.e. dyspnoea at rest), and unstable
- •ischaemic heart disease will be exclusion criteria from cardiopulmonary exercise testing
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