NCT00827476Unknown1 期
Phase 1 Study to Improve Results of Human Ovarian Transplantation
适应症
干预措施
试验速览
- 阶段
- 1 期
- 入组人数
- 100
- 主要终点
- improving folliculogenesis and oocuyte maturation after ovarian transplantation
研究概览
简要总结
we will perform xenotransplantation and in vitro culture of ovarian tissue from patients undergoing ovarian cortex cryopreservation.
详细描述
Ovarian tissue is removed by laparoscopy and only in patients facing premature ovarian failure due to chemotherapy.Tissue for research will consist either of a small portion (<10%) of the cortex for preservation for young women. another source of ovarian tissue for research will be obtained following consent from family of patients who have died of the disease and have previously frozen ovarian tissue.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 5 Years 至 40 Years（Child, Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •tissue previously obtained
排除标准
- •no tissue available or no consent
研究组 & 干预措施
ovarian transplantation
Experimental
tissue will be used for xenotransplantation or in vitro culture
干预措施: ovarian transplantation (Procedure)
结局指标
主要结局
improving folliculogenesis and oocuyte maturation after ovarian transplantation
时间窗: 2 years
次要结局
未报告次要终点
研究者
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