Improving Human Ovarian Transplantation
Early Phase 1
- Conditions
- Fertility Preservation
- Interventions
- Procedure: ovarian transplantation
- Registration Number
- NCT00827476
- Lead Sponsor
- Hadassah Medical Organization
- Brief Summary
we will perform xenotransplantation and in vitro culture of ovarian tissue from patients undergoing ovarian cortex cryopreservation.
- Detailed Description
Ovarian tissue is removed by laparoscopy and only in patients facing premature ovarian failure due to chemotherapy.Tissue for research will consist either of a small portion (\<10%) of the cortex for preservation for young women. another source of ovarian tissue for research will be obtained following consent from family of patients who have died of the disease and have previously frozen ovarian tissue.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 100
Inclusion Criteria
- tissue previously obtained
Exclusion Criteria
- no tissue available or no consent
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description ovarian transplantation ovarian transplantation tissue will be used for xenotransplantation or in vitro culture
- Primary Outcome Measures
Name Time Method improving folliculogenesis and oocuyte maturation after ovarian transplantation 2 years
- Secondary Outcome Measures
Name Time Method