临床试验/NCT03824366

NCT03824366已完成不适用

Pilot Study of Same-session MR-only Simulation and Treatment With MRI-guided Adaptive Palliative RadioTherapy (MAP-RT)

Washington University School of Medicine2 个研究点分布在 1 个国家目标入组 20 人开始时间: 2019年4月23日最近更新: 2025年1月10日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方: Washington University School of Medicine
入组人数: 20
试验地点: 2
主要终点: Feasibility of Same-session MRI-only Simulation as Defined as More Than 70% of Patients Receiving at Least 70% of Their Scheduled Treatment Fractions on the First On-table Attempt for Each Respective Fraction.

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

This proposed study is unique in that patients will not undergo computed tomography (CT) simulation at any point during their treatment course and will instead have same-session magnetic resonance (MR)-only simulation and treatment planning, on-table, using the adaptive radiotherapy (ART) workflow. In this manner, patients requiring urgent treatment could initiate treatment as early as the day of initial radiation oncology consultation.

研究设计

研究类型: Interventional
分配方式: Na
干预模型: Single Group
主要目的: Treatment
盲法: None

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•Diagnosis of malignancy (biopsy proven or high clinical suspicion with urgent/emergent clinical indications for palliative RT)
•Requires delivery of palliative radiation therapy for the treatment of painful metastasis, hemoptysis, gastrointestinal bleeding, pelvic bleeding, or superior vena cava syndrome/bulky mediastinal disease.
•At least 18 years of age.
•Able to understand and willing to sign an IRB-approved written informed consent document.

排除标准

•Pregnant. Patients of childbearing potential must have a negative pregnancy test within 14 days of study entry.
•Medical contraindication to undergoing MR imaging.

结局指标

主要结局

Feasibility of Same-session MRI-only Simulation as Defined as More Than 70% of Patients Receiving at Least 70% of Their Scheduled Treatment Fractions on the First On-table Attempt for Each Respective Fraction.

时间窗: Completion of enrollment (approximately 29 months)

次要结局

未报告次要终点

研究者

发起方

Washington University School of Medicine

申办方类型

Other

责任方

Sponsor

研究点 (2)

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