Influence of Inhaled Anaesthetics on Rebreathing of Carbon Dioxide When Using an Anaesthesia Gas Reflector (AnaConDa)
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Region Skane
- Enrollment
- 12
- Locations
- 1
- Primary Endpoint
- Volume of carbon dioxide rebreathing from an anesthetic gas reflector
Study Overview
Brief Summary
The purpose is to investigate how the adsorptive capacity of the active carbon filter to carbon dioxide in an anaesthetic gas reflector (AnaConDa) is affected by adding inhaled anaesthetic agent.
The hypothesis is that addition of inhaled anaesthetic agent will affect the amount of adsorption of carbon dioxide to the active carbon and thereby affect rebreathing of carbon dioxide.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Basic Science
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 90 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •elective coronary artery by-pass graft surgery
- •elective valve replacement surgery
- •normal left ventricular ejection fraction on preoperative echocardiography
Exclusion Criteria
- •obstructive lung disease
- •restrictive lung disease
Arms & Interventions
Inhaled anaesthetic agent
The group where the investigators adds inhaled anaesthetic agent when using the anaesthetic gas reflector (AnaConda).
Intervention: Inhaled anaesthetic agent (Other)
Outcomes
Primary Outcomes
Volume of carbon dioxide rebreathing from an anesthetic gas reflector
Time Frame: 2 hours
Tidal carbon dioxide volume rebreathed from an anesthetic gas reflector correlated to concentration of delivered anesthetic gas.
Secondary Outcomes
- Quantification of ventilatory requirements to maintain isocapnia with the use of an anesthetic gas reflector.(2 hours)