Comparison the efficacy of 0.5 % hyperbaric levobupivacaine with 0.5% levobupivacaine plus fentanyl in lower limb orthopaedics surgery under spinal anaesthesia.
Not yet recruiting
- Conditions
- Other spontaneous disruption of ligament(s) of knee, (2) ICD-10 Condition: O||Medical and Surgical,
- Registration Number
- CTRI/2023/02/049704
- Lead Sponsor
- Mandakini katiyar
- Brief Summary
various clinical trials have found that administration of fentanyl with local anaesthetic in spinal anaesthesia prolonged the duration of sensory and motor blockade. however ,there are limited data available on comparing of fentanyl as adjunvant to levobupivacaine in spinal anaesthesia.so we want to compare whether adding fentanyl tolevobupivacaine for spinal anaesthesia would affect the sensory and motor blocks and duration of analgesia.the present work has been undertaken to study and compare the effect provided by fentanyl as adjuvants to levobupivacaine in spinal anaesthesia.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
- ASA GRADE 1 AND 2.
- SCHEDULED FOR ELECTIVE LOWER LIMB ORTHOPAEDICS SURGERIES UNDER SPINAL ANAESTHESIA.
Exclusion Criteria
- LACK OF PATIENTS CONSENT.
- PATIENT REFUSALFOR SPINAL ANESTHESIA.
- 3.HISTORY OF SERIOUS PULMONARY DISEASE,ISCHEMIC HEART DISEASE,RENAL/HEPATIC DYSFUNCTION ,CORONARY ARTERY,OR CERVICAL SPINE DISEASE AND PATIENTS WITH ABNORMAL COAGULATION PROFILE.
- PATIENTS WITH LOCAL SKIN SITE INFECTION.
- 5.PATIENTS WITH HYPERSENSTIVITY TO ANY OF THE DRUGS USED.
- 6.PREGNANT AND LACTATING MOTHERS.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method â—To study and compare the onset of analgesia, duration of sensory blockade , motor blockade, hemodynamics parameters ( SBP,DBP,MAP,HR) of 0.5% hyperbaric levobupivacaine and 0.5% hyperbaric levobupivacaine with fentanyl. first 24 hour at immediately after block,at 5min,10min,15min,20 min,25min ,30 min,60 min,90min,120 min,180 min,240 min ,300min.
- Secondary Outcome Measures
Name Time Method to compare the side effects of 0.5% hyperbaric levobupivacaine and 0.5% hyperbaric levobupivacaine with fentanyl.
Trial Locations
- Locations (1)
Peoples college of medical science and research center
🇮🇳Bhopal, MADHYA PRADESH, India
Peoples college of medical science and research center🇮🇳Bhopal, MADHYA PRADESH, IndiaMandakini katiyarPrincipal investigator09769422467mandakinikatiyar.23@gmail.com