TCTR20231019005
Recruiting
Phase 1
Effect of Mozart K.448 on interictal epileptiform discharges in drug-resistant adult epilepsy patients in King Chulalongkorn Memorial hospital
Chulalongkorn Comprehensive Epilepsy Center of Excellence0 sites30 target enrollmentOctober 19, 2023
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Drug-resistant epilepsy
- Sponsor
- Chulalongkorn Comprehensive Epilepsy Center of Excellence
- Enrollment
- 30
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\.Age more than 18 years old
- •2\.Drug\-resistant epilepsy was diagnosed
- •3\.Stable antiseizure medication dose for 1 months before inclusion
Exclusion Criteria
- •1\.Patients who refused to participate in the research
- •2\.Patients who cannot do an EEG according to the 10\-20 principle, such as patients undergoing cranial surgery.
- •3\.Patients with hearing impairment
- •4\.Patient was diagnosed with epilepsy caused by progressive neurological disease such as Rasmussen's encephalitis, mitochondrial disorders, inborn error of metabolism, autoimmune\-associated epilepsy, etc.
- •5\.Patients who tend to be unable to tolerate listening to Mozart K.448, such as those with intellectual disabilities and accompanying behavioral problems.
- •6\.In the first 4\-hour EEG recording during the first night of the study, there were fewer than 10 interictal epileptiform discharges.
- •7\.The patient has a history of irregular heart rhythm known as atrial fibrillation.
- •8\.The patient has a history of having a permanent pacemaker (PPM) implanted.
Outcomes
Primary Outcomes
Not specified
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