Enhancement of a Psychotherapeutic Intervention Through Transcranial Direct Current Stimulation (tDCS)
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- Psychopathological Assessment
研究概览
简要总结
Transcranial Direct Current Stimulation (tDCS), is a neuromodulatory technique, that is safe, well-tolerated, easy to administer and fairly inexpensive. Results from tDCS trials involving participants with several neuropsychiatric disorders, including major depression, bipolar disorder, schizophrenia and substance use disorder are encouraging. The clinical effects of tDCS are broad; the underlying condition, the areas stimulated together with the type and duration of stimulation are important factors. In patients with neuropsychiatric conditions, a reduction of symptoms, an enhancement of neurocognitive functions together with an overall improvement in functionality and wellbeing have been consistently reported. These effects emerge during the stimulation period, in the weeks after stimulation, the effects seem to peak and consolidate further. tDCS appears to enhance the effects of other interventions as well; however, to date, there have been no studies into the effects of using tDCS as an add-on intervention to psychotherapy on symptoms and wellbeing
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Participants are competent to give informed consent, as determined by the referring physician or psychiatrist.
- •German language proficiency as a native speaker or level B1
- •A psychiatric diagnosis according to ICD-10;
- •Three or more psychiatric hospitalizations in the past 12 months; or
- •A cumulative length of stay over 40 days; or
- •Referral for further treatment to our treatment unit.
排除标准
- •Concomitant group psychotherapeutic intervention.
- •Current neurological disorder.
- •Current cardiovascular disorder.
- •Current respiratory disorder.
- •Current substance use or withdrawal.
- •Epilepsy.
结局指标
主要结局
Psychopathological Assessment
时间窗: Change: Baseline, 3, 6 weeks, 6 and 12 months
Symptom Questionnaire
次要结局
- Insecurity- Self-confidence(Change: Baseline, 3, 6 weeks, 6 and 12 months)
研究者
Stephan T. Egger
Senior Psychiatrists
Psychiatric University Hospital, Zurich