NCT01182155已完成不适用
Breath Analysis for Evaluation of Radiation Exposure in Lung Cancer Patients Treated With Radiation: A Feasibility Study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Pre and post-radiation FeNO (fraction of exhaled nitric oxide) measurements
研究概览
简要总结
Patients treated with radiation therapy for lung tumors can experience inflammation after treatment. This study hopes to evaluate the use of breath analysis to evaluate changes in the composition of exhaled breath in patients undergoing radiotherapy. If changes can be detected, this may ultimately serve as biomarkers for identifying patients at highest risk for radiation-induced lung injury (radiation pneumonitis).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of any type of lung tumor
- •Medical recommendation (independent of the study) that the patient undergo thoracic radiation therapy. Radiation therapy may be either fractionated or hypofractionated (i.e. radiosurgery)
- •Age >= 18 years old
- •Any gender and any ethnic background will be recruited
- •Capable of giving written informed consent
排除标准
- •Inability of giving written informed consent
- •Pregnancy or breast-feeding
结局指标
主要结局
Pre and post-radiation FeNO (fraction of exhaled nitric oxide) measurements
时间窗: Every 3 months for 1 year
次要结局
- Pre and post-radiation CO (carbon monoxide), CO2 (carbon dioxide), and N2O (nitrous oxide) measurements and feasibility as the fraction of patients unable to give a breath sample. Adverse events are not expected but any that appear related to the breath(1 yr)
研究者
研究点 (1)
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