Assessment of the effect of guided mindfulness meditation on sensory hypersensitivity and cognitive function in patients with migraine, irritable bowel syndrome, and fibromyalgia: a randomized controlled study with extended follow-up

This is a prospective randomized controlled study designed to evaluate the effect of guided mindfulness meditation on sensory hypersensitivity and cognitive function in patients diagnosed with migraine with comorbid irritable bowel syndrome and fibromyalgia. Eligible participants aged 18 to 80 years will be randomly allocated to either a guided mindfulness meditation intervention group or a control group receiving standard care. The intervention group will undergo structured mindfulness meditation sessions for a predefined duration, while the control group will continue routine clinical management. Outcome measures will include changes in sensory hypersensitivity scores and cognitive function assessed at baseline and predefined follow up intervals. Secondary outcomes will include headache related disability and quality of life measures. The study aims to assess the feasibility and effectiveness of mindfulness based intervention as an adjunctive non pharmacological therapy in this patient population.