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Clinical Trials/NCT03382769
NCT03382769
Terminated
N/A

Hearing Loss in Older Adults: A Randomized Controlled Trial of Immediate Versus Delayed Cochlear Implantation.

Cochlear8 sites in 1 country1 target enrollmentMarch 27, 2019

Overview

Phase
N/A
Intervention
Not specified
Conditions
Hearing Loss, Sensorineural
Sponsor
Cochlear
Enrollment
1
Locations
8
Primary Endpoint
Hearing Handicap
Status
Terminated
Last Updated
3 years ago

Overview

Brief Summary

This is a prospective, 1:1 randomized controlled trial of immediate versus delayed cochlear implantation (CI) on hearing handicap, communicative function, loneliness, mental wellbeing, and cognitive functioning. Participants are randomized 1:1 to an immediate cochlear implant intervention group versus a hearing aid control intervention.

Registry
clinicaltrials.gov
Start Date
March 27, 2019
End Date
January 4, 2020
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Cochlear
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Community-dwelling
  • Proficient in English
  • Oral communicator
  • PTA (500, 1000 \& 2000 Hz) ≥ 70 dB HL hearing loss duration ≥1 and no more than 30 years
  • Active daily hearing aid users
  • HHIE-S score greater than or equal to 24
  • MoCA score greater than or equal to 20
  • Post-linguistic onset sensorineural hearing loss and meet applicable FDA and/or Medicare candidacy criteria for cochlear implantation
  • Willing to consent for the study, to be randomized to either group, to utilize bimodal hearing for the duration of the trial (if clinically appropriate), and follow the study protocol

Exclusion Criteria

  • Prelingual or perilingual severe-to-profound hearing loss
  • Previous cochlear implantation in either ear
  • Hearing loss of neural or central origin
  • Permanent conductive hearing impairment (e.g. otosclerosis)
  • Medical, audiological, or psychological conductions that might contraindicate participation in the clinical investigation
  • Self reported disability in 2 or more activities of daily living
  • Vision impairment worse than 20/40 on a near vision card

Outcomes

Primary Outcomes

Hearing Handicap

Time Frame: 6 months after enrollment

The SSQ-12 is comprised of 12 items using the response format on a scale from 0 to 10, were 0 equals no ability and 10 equals perfect ability. These are divided into three sub-scales and the questions 1-5 are from the speech sub-scale, 6-8 from the spatial, and 9-12 from the qualities sub-scale. The three sub-scales are the average of the questions within. A 'not applicable' option is given for each item. Assessment of the impact of cochlear implantation versus continued hearing aid is then calculated and the theoretical score could vary between -10 to + 10. The higher the score the better benefit and positive score indicates improved hearing, a negative value an impaired hearing.

Study Sites (8)

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