NL-OMON26201
Completed
Not Applicable
The identification of the optimal treatment strategy for complex appendicitis in the pediatric population; CAPP study
Amsterdam UMC0 sites1,308 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- <p>Acute complex appendicitis</p>
- Sponsor
- Amsterdam UMC
- Enrollment
- 1308
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Eligible for inclusion are all children \<18 years old that need to undergo treatment for the suspicion of complex appendicitis. Suspicion of complex appendicitis is based upon the following predefined criteria: \- 4 or more points on our scoring system developed to predict complex appendicitis. This scoring system consists of five variables (clinical, biochemical and radiological, each awarded points). In case the total score is 4 or more points, the patient is likely to have complex appendicitis. Variables included in the scoring system are: \- Diffuse abdominal guarding (3 points) \- CRP level more than 38 mg/L (2 points) \- Signs on ultrasound / imaging indicative for complex appendicitis (2 points) \- More than one day abdominal pain (2 points) \- Temperature more than 37\.5 degrees Celsius (1 point) Or \- High index of suspicion of complex appendicitis by the treating physician. If this is the case, the treating physician will make pre\-treatment note upon what clinical, biochemical or radiological variable the high index of suspicion is based. Classification into the two subgroups of complex appendicitis will be based upon clinical and radiological features. If signs suggestive of perforated appendicitis AND intra\-abdominal abscesses or enlarged mass formation are present, patients will be categorized as subgroup 2\. If no abscess or enlarged mass is present on clinical exam and/or additional imaging, patients will be categorized as subgroup 1\.
Exclusion Criteria
- •1\. Adult patients (\=18 years old) 2\. Children with a suspicion of simple appendicitis (based upon the previous mentioned scoring system and radiological features)
Outcomes
Primary Outcomes
Not specified
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