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Clinical Trials/NCT05110456
NCT05110456
Completed
N/A

Starting Before Birth to Prevent Maternal Mental Health Problems: "Parents and Babies" Program (Programme "Toi, Moi, Bébé")

St. Justine's Hospital1 site in 1 country510 target enrollmentNovember 9, 2021

Overview

Phase
N/A
Intervention
Access to an online cognitive behavioural intervention without telephone support
Conditions
Depression, Postpartum
Sponsor
St. Justine's Hospital
Enrollment
510
Locations
1
Primary Endpoint
Change from baseline at 3 month postpartum depressive symptoms: The Edinburgh Perinatal/Postnatal Depression Scale (EPDS)
Status
Completed
Last Updated
2 months ago

Overview

Brief Summary

Women's perinatal mental health problems can create a cascade of short- and long-term negative influences for the mother, child, and the family as a whole. To prevent these impacts, preventive online and telephone interventions exist, but need to be tested and improved to develop this type of support to women in Quebec. The Parents & Babies program, which is a distance learning course, followed during pregnancy and accompanied by telephone follow-up, aims to improve the mental health of future parents.The investigators seek to evaluate the effect of the intervention of the Parents & Babies program offered with telephone support compared to the course offered without telephone follow-up.

Detailed Description

The Parents \& Babies intervention to be evaluated is an adaptation of the existing, evidence-based Mothers \& Babies program which has shown efficacy in four clinical trials for the prevention of postpartum depression through in-person (group or individual) counseling The Parents \& Babies program was adapted to be virtual and include: 1) specific modules for the mother-partner dyad; 2) third-wave cognitive behavioral therapy (CBT) strategies targeting well-being, relaxation, mindfulness, self-compassion, and gratitude; 3) confinement and social distancing related material. Participants follow the program online or with a paper workbook and are called weekly by a member of the intervention team. Participants will fill out three questionnaires (online or by telephone) at 12-25 weeks' gestation, 3 months' postpartum and 6-months postpartum to assess baseline values and trial outcomes, respectively.

Registry
clinicaltrials.gov
Start Date
November 9, 2021
End Date
September 30, 2024
Last Updated
2 months ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Sponsor
St. Justine's Hospital
Responsible Party
Principal Investigator
Principal Investigator

Sylvana M Côté

Researcher at the research center of the university hospital of saint justine

St. Justine's Hospital

Eligibility Criteria

Inclusion Criteria

  • Pregnant women (12-25 weeks' gestation)
  • subclinical and clinical levels of depression (Edinburgh Postnatal Depression Scale (EPDS) scores 8-16)
  • ability to read and understand French.

Exclusion Criteria

  • EPDS score in the clinical range (≥ 17) or no symptoms (EPDS \< 8)
  • Positive screening of psychotic symptoms using the Psychosis Screening Questionnaire (PSQ)
  • self-reported substance abuse problems.

Arms & Interventions

Access to an online cognitive behavioural intervention without telephone support

The control group will receive a fully automated version of the virtual intervention without telephone support

Cognitive-Behavioral Therapy (CBT) and interpersonal counseling with telephone support.

The experimental group will receive an online cognitive behavioural intervention with weekly telephone support

Intervention: Telephone support

Outcomes

Primary Outcomes

Change from baseline at 3 month postpartum depressive symptoms: The Edinburgh Perinatal/Postnatal Depression Scale (EPDS)

Time Frame: baseline (between gestational weeks 12-25) , 3 months postpartum

The Edinburgh Perinatal/Postnatal Depression Scale (EPDS) assesses a score between 0 and 30. A score less than 8 means depression is unlikely. A score from 9 to 11 means depression is possible. A score from 12 to 13 means high possibility of depression. A score of 14 and higher means probable depression.

Secondary Outcomes

  • Change from baseline in Generalized Anxiety Disorder questionnaire (GAD-7) score(baseline (between gestational weeks 12-25) , 3 and 6 months postpartum)
  • Sleep: Pittsburgh Sleep Quality Index (PSQI)(3 months postpartum)
  • Anxiety related to pregnancy: Pregnancy-specific anxiety scale (PRAQ-R2)(baseline (between gestational weeks 12-25))
  • Well-being: WHO-5 (World Health Organization) index(3 months postpartum)
  • Self-efficacy: General Self-Efficacy scale (GSE)(3 months postpartum)
  • Depressive symptoms: The Edinburgh Postnatal Depression Scale (EPDS)(6 months postpartum)
  • Stress: Perceived Stress Scale (PSS)(6 months postpartum)
  • Self-compassion: Self-Compassion Scale (SCS)(3 months postpartum)
  • Social support: Social Provisions(6 months postpartum)
  • Parenting practices: Parenting Cognitions and Behaviors Scale(6 months postpartum)
  • Child's temperament: Difficult Temperament Scale(6 months postpartum)
  • Personality disorders symptoms: Personality Inventory for DSM-5 Brief Form (PID-5 BF)(baseline (between gestational weeks 12-25))
  • Social Adjustment: Social Adjustment Scale - Self-report (SAS-SR)(3 months postpartum)
  • Marital satisfaction: Short Form of the Dyadic Adjustment Scale (DAS-7)(3 months postpartum)
  • Change from 3 months post-partum at 6 month post partum child social, emotional and cognitive development: Ages and stages questionnaire 3rd edition (ASQ-3)(3 and 6 months postpartum)
  • Co-parenting: Co-parenting Relationship Scale (CRS)(3 months postpartum)
  • Gender roles: Bem Sex Role Inventory (BSRI)(6 months postpartum)

Study Sites (1)

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