Evaluation the efficacy of orthodontic adhesive containing titanium dioxide and chitosan nano-particles in fixed orthodontic patients
Phase 3
- Conditions
- Demineralization of tooth enamel.
- Registration Number
- IRCT20180826040866N1
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Orthodontic patients aged between 13-18 years undergoing fixed orthodontic treatment
Healthy gum
Upper second premolars and upper lateral incisors of the participants to be free of macroscopic enamel cracks, caries, or enamel hypoplasia.
Exclusion Criteria
Patients taking medications that cause xerostomia.
Systemic disease or active periodontal disease
Active caries on at least one tooth
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Population of Sterptococcus Mutans. Timepoint: 24 hours, 2 months and 6 months after placing brackets. Method of measurement: Real-time polymerase chain reaction.
- Secondary Outcome Measures
Name Time Method ?Determination of mineral context of enamel. Timepoint: 24 hours, 2 months and 6 months after placing brackets. Method of measurement: Quantitative laser fluorescence technique.