Choices and Experiences Around Closed-loop Therapy in Type 1 Diabetes

Recruiting

• Conditions: Diabete Mellitus; Type 1 Diabetes Mellitus

• Registration Number: NCT07177404
• Lead Sponsor: University of Nottingham

Brief Summary

Type 1 diabetes requires a lot of work to try to keep glucose levels in the target range. Hybrid closed- loop, also known as artificial pancreas, takes glucose readings from a sensor (continuous glucose monitor) and uses an algorithm to tell an insulin pump how much insulin to deliver. Hybrid closed-loop has currently been rolled out to many people with type 1 diabetes in England. We are keen to develop a deeper understanding of the perspective of people living with type 1 diabetes who have choices about which hybrid closed-loop systems fit their needs.

The main purpose of this study is to explore the choices and experiences of people living with type 1 diabetes regarding closed-loop therapy.

Detailed Description

This is a cross-sectional online survey study, which involves people with type 1 diabetes who use closed-loop, wait to start closed-loop or considering closed-loop.

The primary objective of the study is to explore the factors driving the choices of people living with type 1 diabetes regarding closed-loop therapy.

The secondary objectives of the study are:

* To understand what treatment satisfaction with closed-loop therapy means to people living with type 1 diabetes

* To understand what additional support is needed for people with type 1 diabetes using closed-loop therapy

Study Timeline

• Status Verified: 2025-09
• Study Start: 2025-09-01
• Study First Submitted: 2025-09-01
• Study First Submitted QC: 2025-09-09
• Last Update Submitted: 2025-09-09
• Study First Posted: 2025-09-17
• Last Update Posted: 2025-09-17
• Primary Completion: 2026-02
• Study Completion: 2026-02-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Age: ≥18 years (no upper age limit)
• Type 1 diabetes (any duration)
• People who use closed-loop therapy or wait to start closed-loop therapy or considering closed-loop therapy in the future
• Ability to give informed consent

Exclusion Criteria

• Any other type of diabetes apart from type 1 diabetes

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Ranking of factors influencing the choice of closed-loop therapy among people with type 1 diabetes	At the time of survey completion (single assessment)

Secondary Outcome Measures

Name	Time	Method
Ranking of factors contributing to treatment satisfaction with closed-loop therapy	At the time of survey completion (single assessment)
Distribution of responses to 5-point Likert scale questions assessing factors contributing to treatment satisfaction with closed-loop therapy	At the time of survey completion (single assessment)
Distribution of responses to 5-point Likert scale questions assessing the support needs of people using closed-loop therapy	At the time of survey completion (single assessment)
Associations of demographics and reported glucose levels with factors influencing the choice of closed-loop therapy	At the time of survey completion (single assessment)
Associations of demographics and reported glucose levels with factors contributing to treatment satisfaction with closed-loop therapy	At the time of survey completion (single assessment)
Associations of demographics and reported glucose levels with support needs related to closed-loop therapy	At the time of survey completion (single assessment)

Trial Locations

Locations (1)

University Hospitals of Derby and Burton; 🇬🇧 Derby, United Kingdom