跳至主要内容
临床试验/NCT05208931
NCT05208931已完成不适用

Development of an Algorithm for Predicting Anatomical and Functional the Results of Therapy With Angiogenesis Inhibitors in Patients With Retinal Pigment Epithelium Detachments in Neovascular Age-related Macular Degeneration, Based on Primary Optical Coherence Tomography of the Macular Zone and Clinical Data.

The S.N. Fyodorov Eye Microsurgery State Institution1 个研究点 分布在 1 个国家目标入组 300 人开始时间: 2021年11月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
300
试验地点
1
主要终点
Prediction algorithm

研究概览

简要总结

The study involves the development of an algorithm for predicting anatomical and functional results of therapy with angiogenesis inhibitors in patients with retinal pigment epithelium detachments in neovascular age-related macular degeneration, based on primary optical coherence tomography of the macular zone and clinical data.

详细描述

Patients were divided into 3 groups according to the results of therapy: adhesion of detachment, lack of adherence to detachment, rupture of detachment. For these groups, OCT images of the macular zone with maximum detachment before therapy are selected. These images, along with other clinical parameters, are input to the algorithm. The result is one of the 3 treatment outcomes listed above. The methods that will be used to develop the algorithm include methods for processing and transforming data, deep machine learning, metrics for calculating the accuracy of algorithms.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者
是

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

Prediction algorithm

时间窗: 1.09.2022

Neural network classifier

次要结局

未报告次要终点

研究者

发起方
The S.N. Fyodorov Eye Microsurgery State Institution
申办方类型
Other Gov
责任方
Principal Investigator
主要研究者

Viktoria Myasnikova

Deputy Director for Research

The S.N. Fyodorov Eye Microsurgery State Institution

研究点 (1)

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