The effect of letrozole and methformin on endometrial histology in patients with disordered proliferative endometrium and simple hyperplasia utreus cancer.
Phase 2
- Conditions
- Patients with abnormal bleeding and endometrial proliferative and Hayprplastyk with irregular glands.Endometrial glandular hyperplasia
- Registration Number
- IRCT201412085563N6
- Lead Sponsor
- Vice chancellor for Research,Tabriz University Of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 90
Inclusion Criteria
Patients with abnormal uterine bleeding and havingdisordered proliferative or hyperplastic endometrium and uterine cancer;Consent to participate
Exclusion criteria:People who are allergic to metformin and letrozole, severe impairment of hepatic function; Uncontrolled high blood pressure; Thromboembolism
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Histologic types of endometrial. Timepoint: Three months after the first dose. Method of measurement: Microscopic examination.
- Secondary Outcome Measures
Name Time Method