Homeopathy in the integrative treatment of knee osteoarthritis

Not Applicable

Recruiting

• Conditions: Knee osteoarthritis; C05.550.114.606.500

• Registration Number: RBR-8jc5dp
• Lead Sponsor: nidade de Saúde Escola da Universidade Federal de São Carlos

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-07-23
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Women and men 50 to 75 years old with a knee osteoarthritis diagnosis (according to the American College of Rheumatology criteria) in at least one knee compartment (tibiofemoral and/or patellofemoral).

Exclusion Criteria

Grade 1 or 4 in Kellgren and Lawrence radiologic classification of osteoarthritis; other inflammatory chronic diseases with musculoskeletal impairment; regular use of duloxetine or similar; use of anti-inflammatory drugs. Analgesic scape medication will be allowed.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
In the group initially treated with homeopathy, we expect to find a 30% improvement of reported pain at week 12 (in relation to basal values), assessed through Visual Analog Scale for pain.

Secondary Outcome Measures

Name	Time	Method
Compared to basal values, we expect to observe improvement in pain and mobility in all included patients at weeks 12 and 28. We also expect that that improvement will be significantly superior during homeopathy treatment periods, compared with placebo. Endpoints will be assessed by the following measures: Visual Analog Scale for pain; WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index); 40 meters fast paced walk test; Timed up and go test; 30 seconds chair-stand Test; analgesics load. Adverse Events will be registered throughout the entire study.