E-COMPARED - internet-supported CBT for depressio

Not Applicable

Completed

• Conditions: Major depressive disorder; Mental and Behavioural Disorders

• Registration Number: ISRCTN12388725
• Lead Sponsor: ondon School of Hygiene and Tropical Medicine

Brief Summary

2016 Protocol article in http://www.ncbi.nlm.nih.gov/pubmed/27488181 2020 Results article in https://pubmed.ncbi.nlm.nih.gov/32967872/ Qualitative working alliance results (added 25/09/2020) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35876079/ Practitioners' experience of the working alliance (added 26/07/2022) 2024 Results article in https://doi.org/10.2196/47515 Secondary Data Analysis (added 03/06/2024)

Detailed Description

Not available

Study Timeline

• Study Start: 2015-05-19
• Study Completion: 2016-12-31
• Last Update Posted: 18 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

1. 18 years of age or older
2. Scoring more than 5 points on PHQ-9
3. Meet DSM-IV diagnostic criteria for Major Depression Disorder as confirmed by the telephone administered MINI International Neuropsychiatric Interview version 5.0

Exclusion Criteria

1. Current high risk for suicide according to the MINI Interview section C
2. Serious psychiatric co-morbidity that requires alternative treatment including substance dependence, bipolar affective disorder, psychotic illness or obsessive compulsive disorder as established at the MINI interview
3. Currently receiving psychological treatment for depression in primary or specialised mental health care
4. Being unable to comprehend, speak, read or write English
5. Not having access to a fast internet connection (i.e., broadband or comparable)
6. Not having or being unable to set up an email address that can be used to communicate with the therapist and research team

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome measure will be Patient Health Questionnaire-9 (PHQ-9). The PHQ-9 is a nine-item mood module that can be used to screen and to diagnose patients with depressive disorders. Outcomes will be measured on both arms at baseline, end of treatment (12 weeks), 6 months and 12 months.