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Clinical Trials/NCT02882152
NCT02882152
Completed
Not Applicable

Continuous Femoral Nerve Blockade and Single Shot Sciatic Nerve Block Compared to Intrathecal Morphine for Total Knee Arthroplasty

University of Sao Paulo General Hospital0 sites40 target enrollmentAugust 2011
ConditionsKnee Injuries

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Knee Injuries
Sponsor
University of Sao Paulo General Hospital
Enrollment
40
Primary Endpoint
Analgesic Efficacy
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

Knee arthroplasty has a high potential for postoperative pain. This study compares analgesia and postoperative bleeding from intrathecal morphine with the continuous femoral and a single-shot sciatic nerve blockades.

Detailed Description

This study aims to compare intrathecal morphine as a technique for analgesia with the femoral nerve blockade associated with a single-shot sciatic nerve blockade. Analgesic efficacy, the incidence of adverse effects, and postoperative bleeding were evaluated

Registry
clinicaltrials.gov
Start Date
August 2011
End Date
September 2014
Last Updated
9 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients aged over 18 years old, American Society of Anesthesiologists (ASA) physical status from I to III who underwent total knee arthroplasty

Exclusion Criteria

  • Patients aged below 18 years old, ASA IV or V physical status, infection near the puncture site, coagulation disorders, preexisting neurological disorders, allergy report to local anesthetics, pregnancy and lactation, contraindications to spinal block and refusal to sign an informed consent form

Outcomes

Primary Outcomes

Analgesic Efficacy

Time Frame: baseline (zero hour: discharge of post-anesthesia care unit-PACU), 24hs, 48hs, 72 hours

Pain with verbal numeric rating scale (VNRS). VNRS has 11 points, from zero to 10 (zero= no pain, 1-3 = mild pain, 4-5 = moderate pain, 7-9 = severe pain, 10 = unbearable pain).

Secondary Outcomes

  • Postoperative Bleeding(baseline (discharge of post-anesthesia care unit-PACU), 24hs, 48hs, 72 hours)

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