Can we get conscious sedation in optimal safety conditions in an emergency department, by combining dexmedetomidine with alfentanil?

Cliniques universitaires Saint Luc0 个研究点目标入组 240 人开始时间: 2014年11月24日最近更新: 2020年11月3日

适应症

试验速览

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•Adult over 18 years, of both sexes, for which a procedural sedation is needed in emergency room. The rules for sedation, in accordance with the international guidelines, are:
•Insertion of a chest drain
•Abscess incision and drainage
•Electrical cardio version
•Closed reduction of a dislocated joint
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 140
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 100

•-Patients refusing to participate in the study (refusal to sign the consent form)
•-Patients refusing sedation
•-Patients unable to participate in the study (consent is impossible to obtain)
•-Pregnant women
•-Patients with poor respiratory status determined by :
•Respiratory rate > 30 / min
•Oxygen saturation <90%
•- Patients with unfavorable hemodynamic status determined by :
•A heart rate > 120 / min
•A heart rate < 45 / min
•Systolic blood pressure = 180 mmHg or =100mmHg
•Diastolic blood pressure = 110mmHg
•- Patients with contraindication to the use of dexmedetomidine :
•Advanced heart block (level 2 or 3) unless pacemaker
•Acute cerebrovascular disease

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