A comparative clinical trial to assess the effect of Marichyadi Taila and phototherapy in Mandal Kushtha with special reference to Twak Sharir
Trial Snapshot
- Phase
- Phase 2/3
- Status
- Recruiting
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- Changes in PASI Score
Study Overview
Brief Summary
The prevalence of Psoriasis in India as well as globally is quite high. The report of the prevalence of Psoriasis in countries ranges from 0.09% to 11.43% and making Psoriasis a serious global problem with at least 100 million individuals affected worldwide. Prevalence studied from India are mostly hospital-based which is reported to be 8%. Mandal Kushtha or Psoriasis is difficult to cure as per Ayurveda as well as modern means of treatment. Kushtha or skin diseases are chronic i.e., Kashtasadhya. It affects cosmetically which disturbs the patient from a psychological point of view. Modern medical procedures and treatments have a lot of adverse effects on the Liver, Kidney, Bone marrow, and Skin itself. Apart from this, generally, topical steroids are expensive, and sometimes poor patients cannot afford this treatment. Hence there is a need to search for better methods for the management of Psoriasis.
AIM: -
To assess the effect of Marichyadi Taila and Phototherapy in Mandal Kushtha with special reference to Twak Sharir.
OBJECTIVE: -
Ø To study the physio-pathology of Twak Sharir with special reference to Mandal Kushtha.
Ø To study the effect of Phototherapy on Mandal Kushtha
Ø To compare the effect of Marichyadi Taila and Phototherapy in Mandal Kushtha with special reference to Twak Sharir.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- None
Eligibility Criteria
- Ages
- 18.00 Year(s) to 60.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Subjects with the classical features of Mandal Kushtha.
Exclusion Criteria
- •Subjects suffering from known cases of other systemic disorders such as Cardiac Problems, Uncontrolled Diabetes mellitus, Uncontrolled Hypertension, Paralysis, Malignancy, HIV, HBsAg, Leprosy, etc.
- •Pregnant, lactating mothers.
Outcomes
Primary Outcomes
Changes in PASI Score
Time Frame: 8 weeks
Secondary Outcomes
- Changes in classical signs & symptoms of Mandal Kushta(6 weeks)
Investigators
DrManoj Kumar Gurawa
National Institute of Ayurveda